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Research Article: Intralesional Axitinib Injection Mitigates Hypertrophic Scar by Inhibiting Angiogenesis Pathway: A Preliminary Study in a Rabbit Ear Model

Date Published: 2023-10-24

Introduction:
Hypertrophic scar (HS) is a difficult clinical challenge to tackle with. HS usually develops following burns, trauma or surgery, and it is characterized with disorganized structure and abnormal biomechanical property. It frequently causes aesthetic issues, itching, and pain, restricts mobility of the joints, impairs tissue growth and even leads to psychosocial consequences. HS can significantly reduce the quality of life for patients, there is yet a lack of standardized antiscar protocol to date. Each of the…

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