Research Article: Antrodia cinnamomea May Interfere with the Interaction Between ACE and SARS-CoV- Spike Protein in vitro and Reduces Lung Inflammation in a Hamster Model of COVID-
Introduction:
Severe acute respiratory syndrome coronavirus (SARS-CoV-), responsible for the COVID- pandemic since , shares a common cell entry receptor known as angiotensin converting enzyme II (ACE) with the SARS-CoV virus from . Research has shown that the initial step in viral infection involves the binding of the viral spike protein to ACE. Studies have revealed that individuals with hypertension, diabetes, or chronic obstructive lung disease exhibit significantly elevated levels of ACE expression in their lung tissues…
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