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Research Article: Major Infections of Newly Diagnosed Childhood-Onset Systemic Lupus Erythematosus

Date Published: 2023-05-24

Introduction:
Systemic lupus erythematosus (SLE) is a multi-systemic disease with heterogenous manifestations causing great morbidity and mortality. Previous studies found that death pattern of SLE was bimodal, and the infection was contributed to its early deaths. , Infections were largely considered a complication of immunosuppressive therapy; however, over .% major infectious events were reported at the time of diagnosis without any immunosuppressive medication. A recent study also showed that the prevalence of major…

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