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Research Article: Hypoconnectivity of the Amygdala in Patients with Low-Back-Related Leg Pain Linked to Individual Mechanical Pain Sensitivity: A Resting-State Functional MRI Study

Date Published: 2023-11-08

Introduction:
Low-back-related leg pain (LBLP) is one of the most common subgroups of low-back pain caused by intervertebral disc degeneration, disc herniation and nerve root compression. Patients with LBLP can exhibit a variety of clinical symptoms, including dull or achy, stinging, burning pain or numbness from the low back to the backs of the thighs and even some pain comorbidities/symptoms, such as anxiety, depression, and cognitive impairment. , Additionally, LBLP patients are usually associated with more serious…

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