Research Article: Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function
Abstract:
Post-stroke depression (PSD) is a common psychiatric disorder after a cerebrovascular insult. PSD is associated with higher mortality, worse recovery, more pronounced cognitive deficits, and lower quality of life than stroke without depression. A prospective study showed that the prevalence of PSD in the acute phase after stroke was .%. In addition, a prospective cohort study from mainland China reported that the prevalence of PSD was .%, .%, and .% at weeks, months, and months after stroke, respectively. Although it is now widely accepted that neurobiological and psychosocial factors are important contributors to PSD, the key molecular mechanisms involved in its pathogenesis need to be further explored.
Introduction:
Post-stroke depression (PSD) is a common psychiatric disorder after a cerebrovascular insult. PSD is associated with higher mortality, worse recovery, more pronounced cognitive deficits, and lower quality of life than stroke without depression. A prospective study showed that the prevalence of PSD in the acute phase after stroke was .%. In addition, a prospective cohort study from mainland China reported that the prevalence of PSD was .%, .%, and .% at weeks, months, and months after stroke, respectively. Although…
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