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Research Article: Correlation of Serum Clara Cell Secretory Protein , Plasma Fibrinogen and Serum Amyloid A with the Severity of Acute Exacerbated COPD and Their Combination in Prognosis Assessment

Date Published: 2023-09-06

Introduction:
Chronic obstructive pulmonary disease (COPD) has tremendous detrimental effects on patients’ quality of life, lung function, disease progression and socioeconomic burden. COPD is known to be triggered by cold weather, pollutants, or irritants and exacerbated by acute respiratory tract infection. Patients in the acute phase of COPD, acute exacerbation COPD (AECOPD), suffer from elevated airway inflammation, which in turn progresses into bronchial mucosal congestion and edema, excessive mucus secretion, smooth…

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