Research Article: S rRNA and Metagenomics Combined with UPLC-Q/TOF-MS Metabolomics Analysis Reveals the Potential Mechanism of Radix Astragali Against Hyperuricemia in Mice
Introduction:
Hyperuricemia is a disease caused by irregular purine metabolism, which is always accompanied by excessive production or abnormal excretion of uric acid (UA). Most notably, the overall incidence of hyperuricemia in China has been increasing over the past decade with the westernization of eating habits. , However, there are blind spots and misunderstandings in its diagnosis, prevention and treatment. Obviously, there are several only UA-lowering medicines in the clinic, such as allopurinol (ALL) and benzbromarone.…
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