Research Article: Insulin Stimulates IL- Expression in Human Adipocytes: A Possible Explanation for the Higher Prevalence of Psoriasis in Obesity
Introduction:
Psoriasis is a chronic systemic immune-mediated inflammatory disease with a prevalence of –% worldwide. Although the etiology of this disease is still not precisely known, its pathogenesis, albeit incompletely, has been clarified and in particular the role of many pro-inflammatory cytokines derived from immune cells and interacting with different tissues leading to the typical lesions affecting the skin. The interleukin-/interleukin- (IL-/IL-) immune axis is considered to have a pivotal role in the pathogenesis of…
Read more