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Research Article: Hepatectomy After Conversion Therapy with Hepatic Arterial Infusion Chemotherapy, Tyrosine Kinase Inhibitors and Anti-PD- Antibodies for Initially Unresectable Hepatocellular Carcinoma

Date Published: 2023-10-04

Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignancies and the third leading cause of cancer-related deaths worldwide. Radical treatments including liver resection, liver transplantation, and radiofrequency ablation have been considered for patients with early-stage HCC. However, most patients are diagnosed at intermediate or advanced stages when they are not candidates for curative resection., Despite various therapies for advanced HCC, including interventional therapies, tyrosine kinase inhibitors (TKIs), and anti-PD- antibodies, survival remains poor, with a -year survival rate of approximately %.

Introduction:
Hepatocellular carcinoma (HCC) is one of the most common malignancies and the third leading cause of cancer-related deaths worldwide. Radical treatments including liver resection, liver transplantation, and radiofrequency ablation have been considered for patients with early-stage HCC. However, most patients are diagnosed at intermediate or advanced stages when they are not candidates for curative resection. , Despite various therapies for advanced HCC, including interventional therapies, tyrosine kinase…

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