Research Article: Molecular Docking Study of Phytosterols in Lygodium microphyllum Towards SIRT and AMPK, the in vitro Brine Shrimp Toxicity Test, and the Phenols and Sterols Levels in the Extract
Abstract:
An epidemiology study reported that lipid disorders such as non-alcoholic liver disease (NAFLD) had reached .% (Africa) to .% (Middle East) of cases. The elevating prevalence of this disease is correlated with the global obesity epidemic and the manifestation of metabolic disorders. Lipid disorders occur due to unhealthy diet patterns such as high fat or high sugar intake and a sedentary lifestyle. People with fatty liver disease are prone to suffer vascular risk and cardiovascular disease progression. The Food and Drug Administration (FDA)-approved drug for NAFLD is limited. Therefore, finding new drugs for NAFLD therapy is challenging.
Introduction:
An epidemiology study reported that lipid disorders such as non-alcoholic liver disease (NAFLD) had reached .% (Africa) to .% (Middle East) of cases. The elevating prevalence of this disease is correlated with the global obesity epidemic and the manifestation of metabolic disorders. Lipid disorders occur due to unhealthy diet patterns such as high fat or high sugar intake and a sedentary lifestyle. People with fatty liver disease are prone to suffer vascular risk and cardiovascular disease progression. The Food…
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