Research Article: Inhibition Effect of Physalis angulata Leaf Extract on Viability, Collagen Type I, and Tissue Inhibitor of Metalloproteinase (TIMP-) but Not Plasminogen Activator Inhibitor- (PAI-) of Keloid Fibroblast Culture
Introduction:
Keloids are benign fibroproliferative tumors that arise because of an abnormal wound healing process. The incidence of keloids varies depending on race. A retrospective study on the overall incidence of keloids after head or neck surgery showed an incidence rate of .% and .% for White American and African Americans, respectively. Keloid impairs the quality of life by causing pain, itchiness, cosmetic impairment, and functional deformity. There is no single effective keloid treatment because of the high recurrence…
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