Research Article: The Effect of Decrease in Serum Urate for the Risk of Gout Flares During Urate-Lowering Therapy Initiation Among Chinese Male Gout Patients: A Prospective Cohort Study
Introduction:
Gout is a common metabolic disorder caused by the deposition of monosodium urate (MSU) crystals in the joints and other tissues. Gout clinically manifests as follows: recurrent acute arthritis, chronic joint swelling, tophus. In severe cases, it may lead to joint deformity and renal failure. The prevalence of gout has risen in China, with a weighted prevalence rate of .% in adults (males for .%, females for .%). Urate-lowering therapy (ULT) is used to reduce serum urate levels to prevent the formation of new MSU…
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