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Research Article: Development and Validation of a Prediction Model for Hepatitis B Virus-Related Hepatocellular Carcinoma Patients Receiving Postoperative Adjuvant Transarterial Chemoembolization

Date Published: 2023-10-24

Abstract:
Hepatocellular carcinoma (HCC), the most prevalent primary liver malignancy, accounts for –% of all liver cancers. The International Agency for Research on Cancer (IARC) has estimated that the morbidity and mortality due to liver cancer ranks sixth and third among all tumors, respectively, thus significantly threatening people’s health., Infection with the hepatitis B virus (HBV) is a significant risk factor for HCC. HBV activates multiple signals, promotes viral replication and inflammatory progression, accelerates liver cancer development, and is correlated with a high mortality rate, especially in Asian China.– Patients with HBV-associated HCC who have undergone liver resection have a poorer prognosis than those with metabolic HCC. Moreover, a nationwide survey found that HCC patients without HBV infection had a noticeably decreased probability of recurrence than those with HBV infection.

Introduction:
Hepatocellular carcinoma (HCC), the most prevalent primary liver malignancy, accounts for –% of all liver cancers. The International Agency for Research on Cancer (IARC) has estimated that the morbidity and mortality due to liver cancer ranks sixth and third among all tumors, respectively, thus significantly threatening people’s health. , Infection with the hepatitis B virus (HBV) is a significant risk factor for HCC. HBV activates multiple signals, promotes viral replication and inflammatory progression,…

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