Research Article: Sarcoplasmic Myxovirus Resistance Protein A: A Study of Expression in Idiopathic Inflammatory Myopathy
Abstract:
Idiopathic inflammatory myopathies (IIM) compose a heterogeneous group of rare autoimmune disorders initially characterized by skeletal muscle inflammation and muscle weakness. Extramuscular involvement (eg skin, lungs, and malignancy) affects a number of patients, making classification more challenging., Muscle-specific autoantibodies (MSAs) have been discovered over recent years and are correlated with specific clinicopathological subgroups. IIM classifications have integrated clinical manifestation, MSA, and pathologic features to categorize IIM into five subgroups: dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM), immune-mediated necrotizing myopathy (IMNM), and antisynthetase syndrome (ASS).–
Introduction:
Idiopathic inflammatory myopathies (IIM) compose a heterogeneous group of rare autoimmune disorders initially characterized by skeletal muscle inflammation and muscle weakness. Extramuscular involvement (eg skin, lungs, and malignancy) affects a number of patients, making classification more challenging. , Muscle-specific autoantibodies (MSAs) have been discovered over recent years and are correlated with specific clinicopathological subgroups. IIM classifications have integrated clinical manifestation, MSA, and…
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