Research Article: A Novel Nomogram for the Preoperative Prediction of Edmondson-Steiner Grade III-IV in Hepatocellular Carcinoma Patients
Abstract:
While the incidence and mortality rates of most cancers are declining, the incidence and mortality rates of hepatocellular carcinoma (HCC) are increasing., It is the second leading cause of cancer-related deaths. Localized HCC is asymptomatic for most of its course. Most HCC patients have advanced disease at first diagnosis and do not qualify for potentially curative treatment. Therefore, early identification of poor prognostic factors and carefully evaluating patient treatment options are critical. The Edmondson-Steiner (E-S) grade has been identified as one of the poor prognostic factors for HCC. However, studies using routine laboratory tests and imaging features to predict the E-S grade are scarce. Since a large sample cohort study demonstrated that HCC patients with E-S grade III–IV could account for .% of all patients, it makes sense to focus on the clinical use of the E-S grade.
Introduction:
While the incidence and mortality rates of most cancers are declining, the incidence and mortality rates of hepatocellular carcinoma (HCC) are increasing. , It is the second leading cause of cancer-related deaths. Localized HCC is asymptomatic for most of its course. Most HCC patients have advanced disease at first diagnosis and do not qualify for potentially curative treatment. Therefore, early identification of poor prognostic factors and carefully evaluating patient treatment options are critical. The…
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