Research Article: Cobalt-Doped Mesoporous Silica Coated Magnetic Nanoparticles Promoting Accelerated Bone Healing in Distraction Osteogenesis
Introduction:
Distraction osteogenesis (DO) is a common orthopaedic technique widely used for large bone defects and congenital or acquired osseous deformities. The DO procedure consists of three sequential phases: the latency phase after osteotomy, the distraction phase to distract the bone ends using a distractor, and the consolidation phase to achieve new bone mineralisation and remodelling. The advantage of DO, compared with other techniques used for bone defect reconstruction, is that it does not require bone tissue…
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