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Research Article: High Contrast Detection of Carotid Neothrombus with Strong Near-Infrared Absorption Selenium Nanosphere Enhanced Photoacoustic Imaging

Date Published: 2023-07-24

Abstract:
Cardiovascular disease accounts for about half of all deaths worldwide, mainly due to the high fatality rate of advanced atherosclerosis., After lipid deposition in the intima of blood vessels, the intima will gradually thicken to form atherosclerotic plaques and will be a danger of falling off at any time. The thrombus is a potentially complicating condition of atherosclerosis. Thrombosis often occurs after atherosclerotic plaque ruptures, which may lead to stroke or acute myocardial infarction. The accumulation of plaque can block blood flow in the carotid arteries, and in severe cases, inadequate blood supply to the brain may lead to an acute stroke event. Approximately one-quarter of all ischemic strokes are cardioembolic, especially in patients with atrial fibrillation, and three-fourths are atherothrombotic, including carotid artery atherosclerotic disease. Despite advances in medical therapies and thrombolysis, the effective treatment of stroke remains elusive for various practical reasons. Therefore, it is essential to familiarize and prevent thrombotic diseases.

Introduction:
Cardiovascular disease accounts for about half of all deaths worldwide, mainly due to the high fatality rate of advanced atherosclerosis. , After lipid deposition in the intima of blood vessels, the intima will gradually thicken to form atherosclerotic plaques and will be a danger of falling off at any time. The thrombus is a potentially complicating condition of atherosclerosis. Thrombosis often occurs after atherosclerotic plaque ruptures, which may lead to stroke or acute myocardial infarction. The accumulation…

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