Research Article: Development and Validation Nomogram for Predicting the Survival of Patients with Thrombocytopenia in Intensive Care Units
Abstract:
Platelets, which are cytoplasmic components shed by megakaryocytes, are one of the main cellular products of the blood and play an important role in hemostasis and coagulation. In healthy individuals, platelets adhere closely to the inner wall of capillaries in order to maintain their structural integrity. Under normal physiological conditions, vascular endothelial cells or blood cells do not interact with each other. However, when the blood vessel wall is damaged, platelets exert their biochemical aggregation and adhesion characteristics. Most platelets exist in the blood and participate in various metabolic processes of the body. A small part of platelets exist in extravascular organs or tissues, such as the spleen. Under certain circumstances, platelets can enter and exit blood vessels and participate in various physiological and pathological metabolic processes of the body.
Introduction:
Platelets, which are cytoplasmic components shed by megakaryocytes, are one of the main cellular products of the blood and play an important role in hemostasis and coagulation. In healthy individuals, platelets adhere closely to the inner wall of capillaries in order to maintain their structural integrity. Under normal physiological conditions, vascular endothelial cells or blood cells do not interact with each other. However, when the blood vessel wall is damaged, platelets exert their biochemical aggregation and…
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