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Research Article: EPAS/HIF-? Acts as an Unanticipated Tumor-Suppressive Role in Papillary Thyroid Carcinoma

Date Published: 2023-05-31

Abstract:
Papillary thyroid carcinoma (PTC) has significantly increased in the world over the past few decades, and it is the third most common solid malignancy. Most patients with PTC anticipated a relatively satisfactory clinical prognosis under the traditional therapy. However, part of PTC patients still posed the surgeons and oncologists a particularly difficult therapeutic challenge. Hence, a further exploration of the underlying molecular mechanisms involved in the unusually high aggressiveness events of PTC patients is clinically significant.

Introduction:
Papillary thyroid carcinoma (PTC) has significantly increased in the world over the past few decades, and it is the third most common solid malignancy. Most patients with PTC anticipated a relatively satisfactory clinical prognosis under the traditional therapy. However, part of PTC patients still posed the surgeons and oncologists a particularly difficult therapeutic challenge. Hence, a further exploration of the underlying molecular mechanisms involved in the unusually high aggressiveness events of PTC patients…

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