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Research Article: The Methylation in B-H and BTLA Genes are Associated with the Risk of Pulmonary Tuberculosis

Date Published: 2023-11-24

Abstract:
Tuberculosis (TB) is a common, serious infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis) infection, which is still a major public health problem. Before the COVID- pandemic, TB was the leading cause of death from a single pathogen, and the most common type of this disease was pulmonary TB (PTB). The COVID- pandemic resulted in reduced access to TB diagnosis and treatment. There were approximately . million new cases of TB worldwide and about . million new cases of TB in China in according to the Global Tuberculosis Report . Studies showed that about a quarter of the population was infected with M. tuberculosis globally, while less than % of those infected would develop active TB. This suggested that the pathogenesis of TB was influenced by multiple factors, including nutrition, immunity, genetic factors, smoke, alcohol, and HIV infection.–

Introduction:
Tuberculosis (TB) is a common, serious infectious disease caused by Mycobacterium tuberculosis ( M . tuberculosis ) infection, which is still a major public health problem. Before the COVID- pandemic, TB was the leading cause of death from a single pathogen, and the most common type of this disease was pulmonary TB (PTB). The COVID- pandemic resulted in reduced access to TB diagnosis and treatment. There were approximately . million new cases of TB worldwide and about . million new cases of TB in China in…

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