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Research Article: Anti-Diabetic Effects of the % Methanolic Extract of Datura Stramonium Linn (Solanaceae) Leaves in Streptozotocin- Induced Diabetic Mice

Date Published: 2023-10-18

Abstract:
Diabetes mellitus is a metabolic disorder characterized by hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Diabetes mellitus is one of the most prevalent metabolic disorders affect million people (ages to ) worldwide and is predicted to affect million people by the year . In Africa million adults aged – years are living with diabetes. The prevalence of diabetes mellitus in Ethiopia is % to .%. It became one of the top listed Sub-Saharan African countries, and % of ?deaths in the country are caused by hyperglycemia and its complication. DM is classified into four broad categories: type DM, type DM, GDM, and other specific types. Diabetes-related chronic hyperglycemia is linked to long-term damage and dysfunction of various organs, mainly the kidneys, eyes, nerves, heart, and blood vessels.

Introduction:
Diabetes mellitus is a metabolic disorder characterized by hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Diabetes mellitus is one of the most prevalent metabolic disorders affect million people (ages to ) worldwide and is predicted to affect million people by the year . In Africa million adults aged – years are living with diabetes. The prevalence of diabetes mellitus in Ethiopia is % to .%. It became one of the…

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