Research Article: Test–Retest Reliability of the Generalized Pain Questionnaire in Patients with Rheumatoid Arthritis and Preliminary Reference Values for Non-Clinical and Several Clinical Samples
Introduction:
A characteristic feature of several different types of chronic pain syndromes is the presence of widespread hypersensitivity to pain, also called generalized pain hypersensitivity. The mechanism underlying this phenomenon is thought to be central sensitization, ie increased responsiveness of nociceptive neurons in the central nervous system to their normal or subthreshold afferent input. Typically, the presence of generalized pain hypersensitivity is probed by performing pain threshold measurements at a local (ie…
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