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Research Article: Total Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NF?B Pathway

Date Published: 2023-09-20

Introduction:
Osteoarthritis (OA) is a common degenerative joint disease characterized by chronic pain and ambulation limitation, affecting about million people worldwide. With increased aging population, the OA incidence rapidly increases and OA has become a major cause of disability. , The morbidity of OA is closely related to articular cartilage, synovium, subchondral bone and surrounding muscles and ligaments, and cartilage plays a critical role in the pathogenesis of OA. – The senescence of chondrocytes, joint trauma and…

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