Research Article: Initiation of Medical Therapy for Heart Failure Patients According to Kidney Function: A Danish Nationwide Study
Abstract:
The management of patients with heart failure (HF) in the presence of kidney dysfunction is complex. The frequent coexistence of these two conditions often results in a poorer prognosis, and patients with heart failure and kidney dysfunction tend to be older, frailer, and have a greater number of comorbidities compared to those without kidney dysfunction.– In addition, when kidney dysfunction is present, as indicated by an estimated glomerular filtration rate (eGFR) of less than mL/min/. m, there is a tendency to underutilize HF therapy, resulting in a risk-treatment paradox. This means that patients who have a higher risk of mortality are actually treated with fewer disease-modifying medical therapies. As patients with HF and coexisting kidney dysfunction, older age, and frailty are considered a high-risk group, it is especially crucial to optimize HF therapy in this population.
Introduction:
The management of patients with heart failure (HF) in the presence of kidney dysfunction is complex. The frequent coexistence of these two conditions often results in a poorer prognosis, and patients with heart failure and kidney dysfunction tend to be older, frailer, and have a greater number of comorbidities compared to those without kidney dysfunction. – In addition, when kidney dysfunction is present, as indicated by an estimated glomerular filtration rate (eGFR) of less than mL/min/. m, there is a tendency to…
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