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Research Article: Diagnostic Performance of Anti-Topoisomerase-I, Anti-Th/To Antibody and Anti-Fibrillarin Using Immunoblot Method in Systemic Sclerosis Related Interstitial Lung Disease Patients

Date Published: 2023-04-28

Introduction:
Systemic Sclerosis (SSc) is an autoimmune disease with progressive chronic characteristics that affects several organs, including skin connective tissue, visceral, and blood vessel walls. Furthermore, the condition is characterized by three primary processes: () endothelial dysfunction, () fibrosis, and () autoantibody production. Previous studies revealed that it is very common among people of productive age, with the highest incidence rate occurring in third to fifth decades of life. Women have also been…

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