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Research Article: Visual Acuity in Aniridia and WAGR Syndrome

Date Published: 2023-05-01

Introduction:
Aniridia is a panocular congenital malformation of the eye featuring complete or partial iris hypoplasia and foveal hypoplasia, resulting in reduced visual acuity. Glaucoma, cataract and keratopathy also may occur in individuals affected with aniridia, which may be associated with further vision loss. – Nearly all cases of aniridia are caused by mutation or deletion of the paired box ( PAX ) gene at p, with resulting haploinsufficiency. , Nonsense PAX mutations were identified in about a third of sequence variants…

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