Research Article: A Novel Nomogram Combining Mucus Barrier Index for Predicting Treatment Failures in Ulcerative Colitis
Abstract:
Ulcerative colitis (UC), a common subtype of inflammatory bowel disease (IBD), is presented with high morbidity universally., Given its frequent relapse and incurable features, UC has evolved as a global burden., Even though it is easier to get control than other IBD patients, a few patients still experience unbeneficial outcomes, such as loss of control under monotherapy or surgical treatment., Even the loss of response to biological intervention by biologic would occur in the unfortunate., Constant transition of therapy is common because of drug resistance or intolerance., Surgery is an unavoidable method for patients presented no response to medications or with identified colorectal neoplasm., Colectomy, as a paradigm surgery for UC, severely affects the patients’ quality of life.
Introduction:
Ulcerative colitis (UC), a common subtype of inflammatory bowel disease (IBD), is presented with high morbidity universally. , Given its frequent relapse and incurable features, UC has evolved as a global burden. , Even though it is easier to get control than other IBD patients, a few patients still experience unbeneficial outcomes, such as loss of control under monotherapy or surgical treatment. , Even the loss of response to biological intervention by biologic would occur in the unfortunate. , Constant…
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