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Research Article: A Disintegrin and Metalloproteinase Protein (ADAM ) in Autism Spectrum Disorder: Links to Neuroinflammation

Date Published: 2023-08-14

Abstract:
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions with repetitive stereotypical behaviors. The etiopathology of ASD is unclear, and no diagnostic or predictive biomarkers have yet been discovered. A diagnosis is achieved using behavioral assessments using various ASD screening and diagnostic methods, including the Diagnostic and Statistical Manual of Mental Disorders, fifth Edition (DSM-V), Childhood Autism Rating Scale (CARS), Social Responsiveness Scale (SRS) and Short Sensory Profile (SSP).– A sudden rise in the prevalence of ASD has encouraged an increase in research studies on the fundamental neuropathologic routes of this disorder. An increasing body of research states that neuroinflammation and dysregulated immune responses are essential pathological processes involved in the etiological pathway of ASD.–

Introduction:
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions with repetitive stereotypical behaviors. The etiopathology of ASD is unclear, and no diagnostic or predictive biomarkers have yet been discovered. A diagnosis is achieved using behavioral assessments using various ASD screening and diagnostic methods, including the Diagnostic and Statistical Manual of Mental Disorders, fifth Edition (DSM-V), Childhood Autism Rating Scale (CARS), Social Responsiveness Scale…

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