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Research Article: Immunomodulation Effect of Convalescent Plasma Therapy in Severe – Critical COVID- Patients

Date Published: 2023-04-24

Introduction:
SARS-CoV- infection causes damage to lung tissue, which triggers a local immune response thereby inducing monocytes and macrophages that release inflammatory cytokines and inducing an adaptive immune response. Inflammatory cytokines such as Interleukin- (IL-), Interleukin- (IL-) and tumor necrosis alpha (TNF-?) play a role in the initial response, while anti-inflammatory cytokines such as Interleukin- (IL-) and Interleukin- (IL-) produced during infection plays a role in immune system homeostasis. Severe…

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