Research Article: Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema
Abstract:
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Introduction:
Ulcerative colitis (UC) is featured with mucosal inflammation that begins with rectum and spreads to the proximal colon. The typical symptoms of UC include abdominal pain, acute or chronic diarrhea, and bloody stools. Pathogenesis of UC is still unclear, and an increasing number of studies suggest that it is mainly caused by immune dysregulation, intestinal epithelial barrier defects, intestinal microbial changes and environmental factors. The popular therapeutic medicines for UC are -aminosalicylic acid (-ASA),…
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