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Research Article: The Efficacy and Safety of Dotinurad on Uric Acid and Renal Function in Patients with Hyperuricemia and Advanced Chronic Kidney Disease: A Single Center, Retrospective Analysis

Date Published: 2023-11-03

Introduction:
Hyperuricemia is an important potential complication of chronic kidney disease (CKD) and is associated with the progression to end-stage renal disease worldwide. , Uric acid (UA) crystals deposition in the renal tubules and interstitials due to hyperuricemia, a condition called urate nephropathy, has been considered to be the cause of the progression of CKD associated with hyperuricemia. UA-lowering drugs have been shown to reduce the UA level and inhibit the renal function decline in asymptomatic hyperuricemic…

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