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Research Article: Retinal Vessel Density and Retinal Nerve Fiber Layer Thickness: A Prospective Study of One-Year Follow-Up of Patients with Parkinson’s Disease

Date Published: 2023-08-22

Introduction:
Parkinson’s Disease (PD), the second-most common neurodegenerative disorder, is characterized primarily by the deposition of ?-synuclein (alpha-synuclein, ?-syn) and subsequent loss of dopaminergic cells in the substantia nigra. Recently, the role of vascular factors in the pathogenesis and progression of PD has come under increasing scrutiny. Studies suggest that individuals with high-risk factors for vascular disease may face elevated risks for PD. In a cohort study of early-stage PD patients, the incidence of…

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