Research Article: Assessment of Fraction of Exhaled Nitric Oxide and Soluble Receptor for Advanced Glycation End Products Biomarkers for Jordanian Asthmatic Children
Introduction:
Asthma is the most common chronic lung disease affecting children worldwide. It is a heterogenous disease comprising a range of different clinically recognized phenotypes that are characterized by bronchial hypersensitivity, chronic airway inflammation and reversible airway narrowing. Asthma is mainly diagnosed based on clinical history and physical findings that are linked to distinct, yet complex underlying molecular pathways known as endotypes. Two major endotypes of asthma were identified, T-helper -high…
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