Research Article: Effect of Frailty on the Long-Term Prognosis of Elderly Patients with Acute Myocardial Infarction
Abstract:
With the aging of the population worldwide, the proportion of elderly patients with cardiovascular diseases (CVDs) is gradually increasing. A recent epidemiological report by the American Heart Association indicates that the prevalence of CVDs is –% in people aged – years old and –% in people aged over years old. Acute myocardial infarction (AMI) is one of the most severe CVDs. Elderly patients with AMI often have multiple comorbidities, a longer hospital stay, and a worse prognosis compared to young patients. However, age is not the only factor affecting the prognosis of patients with AMI. A study by Rizzuto et al has revealed that AMI leads to decreased physiological function in elderly patients.– Frailty, which refers to a clinical state of increased vulnerability and reduced stress resistance resulting from the age-associated decline in physical and cognitive reserve and function, is a reliable indicator for decreased physiological function. The clinical manifestations of frailty include multisystem dysfunction, chronic inflammatory status, cachexia, and muscle loss. How frailty affects the prognosis of elderly patients with AMI warrants further investigation. A study comprising a large sample size of AMI patients aged years and older showed that approximately / of the patients exhibited frailty. Among AMI patients aged years and above, the prevalence of frailty was reported to be between % and %.
Introduction:
With the aging of the population worldwide, the proportion of elderly patients with cardiovascular diseases (CVDs) is gradually increasing. A recent epidemiological report by the American Heart Association indicates that the prevalence of CVDs is –% in people aged – years old and –% in people aged over years old. Acute myocardial infarction (AMI) is one of the most severe CVDs. Elderly patients with AMI often have multiple comorbidities, a longer hospital stay, and a worse prognosis compared to young patients.…
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