Research Article: Plasmatic Levels and Response to Variable Doses of Monthly Aripiprazole and Three-Month Paliperidone in Patients with Severe Schizophrenia. Treatment Adherence, Effectiveness, Tolerability, and Safety
Introduction:
Antipsychotic medications (AP) are an effective maintenance treatment for schizophrenia – and clearly reduce the risk of relapse and hospitalization. – The lack of adherence is associated with relapse and (re)admission, – and risk of suicide. – It has been suggested that second-generation antipsychotics (SGAs) are more effective than first-generation antipsychotics and are also better tolerated and safer, – which is why their use is already widespread. , , , , , – However, there is still debate about the use of…
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