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Research Article: Identification of Hub Genes in the Pathogenesis of Bronchiolitis Obliterans via Bioinformatic Analysis and Experimental Verification

Date Published: 2023-08-08

Abstract:
Bronchiolitis obliterans (BO) is a chronic pulmonary disease characterized by irreversible narrowing of the small airways, which leads to reduced long-term survival after lung transplantation., It is also a common complication in children diagnosed with severe adenovirus pneumonia. While certain diagnosis and treatments were available for BO patients, significant challenges were still present for patients complete recovery, hence the poor prognosis for BO patients. Therefore, efforts to understand the underlying molecular mechanisms of BO may be crucial to provide a significant breakthrough in developing better treatments for patients with BO.

Introduction:
Bronchiolitis obliterans (BO) is a chronic pulmonary disease characterized by irreversible narrowing of the small airways, which leads to reduced long-term survival after lung transplantation. , It is also a common complication in children diagnosed with severe adenovirus pneumonia. While certain diagnosis and treatments were available for BO patients, significant challenges were still present for patients complete recovery, hence the poor prognosis for BO patients. Therefore, efforts to understand the underlying…

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