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Research Article: A Single-Step Immunocapture Assay to Quantify HCC Exosomes Using the Highly Sensitive Fluorescence Nanoparticle-Tracking Analysis

Date Published: 2023-11-02

Introduction:
Primary liver cancers, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), are the leading cause of cancer-related death worldwide. – HCC accounts for –% of primary liver cancer and most often develops in the context of cirrhosis due to viral or non-viral chronic liver disease. The hazard ratios for developing HCC are higher in patients with chronic viral hepatitis due to Hepatitis C (HCV) or Hepatitis B (HBV). HCV infection can be cured with direct-acting antivirals (DAAs) which…

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