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Research Article: Effects of Liver Fibrosis on Islet Function in Patients with Chronic Hepatitis B Complicated with Impaired Fasting Glucose

Date Published: 2023-11-08

Abstract:
Hepatic fibrosis is a crucial step in the progression toward cirrhosis and reflects the deterioration in liver function. Cirrhosis is highly prevalent worldwide, and it often leads to a decline in quality of life and increased mortality. In various chronic liver disease etiologies, cirrhosis develops gradually, involves the entire liver, and is characterized by the accumulation of fibrotic extracellular matrix and nodular regeneration.

Introduction:
Hepatic fibrosis is a crucial step in the progression toward cirrhosis and reflects the deterioration in liver function. Cirrhosis is highly prevalent worldwide, and it often leads to a decline in quality of life and increased mortality. In various chronic liver disease etiologies, cirrhosis develops gradually, involves the entire liver, and is characterized by the accumulation of fibrotic extracellular matrix and nodular regeneration.

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