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Research Article: Effects of microcurrent therapy in promoting function and pain management of knee osteoarthritis: a systematic review and meta-analysis protocol

Date Published: 2023-04-26

Abstract:
Introduction Microcurrent therapy (MCT) is a rising conservative treatment for patients with knee osteoarthritis (OA). Considering its potential benefits and convenience, MCT’s application in those individuals with knee OA is capacious. However, no plausible clinical evidence has proved its unequivocal advantages in treating knee OA conservatively. The purpose of this study is to determine whether MCT is helpful in pain management and promoting function of knee OA and is safe in the treatment of knee OA in adult patients. Methods and analysis We will search through MEDLINE, Embase, Cochrane Library, Web of Science and Google Scholar from inception to 15 March 2023. Original studies will include randomised controlled trials of patients treated with MCT. Two authors will independently screen, select studies, extract data and perform risk of bias assessment. Data consistently reported across studies will be pooled using random-effects meta-analysis. Heterogeneity will be evaluated using Cochrane’s Q statistic and quantified using I 2 statistics. Graphical and formal statistical tests will be used to assess for publication bias. Ethics and dissemination Ethical approval will not be needed for this study as the data will be extracted from already published studies. The results of this review will be published in a peer-reviewed journal and presented at conferences. PROSPERO registration number CRD42022319828

Introduction:
Osteoarthritis (OA) is the most common joint disease and one of the most prominent pathological factors of disability worldwide. 1 Knee OA affected an estimated 654?million individuals in 2020, requiring significant financial support globally. 2 The morbidity of knee OA has a significant impact on quality of daily life and is closely associated with age, sex and financial input in China. 3 Knee OA is primarily a degenerative and progressive disease that mainly affects the elderly and is caused by the loss of…

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