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Research Article: Lifetime risks of second primary malignancies after pediatric Hodgkin lymphoma and non-Hodgkin lymphoma

Date Published: 2024-01-27

Introduction:
With the advent of novel treatments, the life expectancy of lymphoma patients, including pediatric cases, has been significantly extended. However, this progress has given rise to a new and serious concern—the development of second primary malignancies (SPMs). In adult patients, especially those with specific lymphoma subtypes, previous studies have explored the relationships between SPMs and factors such as genetic vulnerability, family history, immunodeficiency, environmental exposure, and various treatment…

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