Research Article: Growth speed of large brain metastases between diagnostic and radiosurgical planning MRI and predictors of rapid tumor growth
Introduction:
Brain metastases are a substantial contributor to overall cancer mortality and poor prognosis in patients with advanced-stage cancer [1]. Conventional whole-brain radiotherapy is an important and widely used brain metastasis treatment modality, particularly in patients with multiple lesions. However, large-field brain radiotherapy is associated with neuropsychological sequelae and deterioration in quality of life [1,2,3]. Therefore, single-fraction stereotactic radiosurgery (sfSRS) has become the preferred…
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