Research Article: Liraglutide Improves Nonalcoholic Fatty Liver Disease in Diabetic Mice by Activating Autophagy Through AMPK/mTOR Signaling Pathway
Abstract:
Type diabetes (TDM) and nonalcoholic fatty liver disease (NAFLD) are common chronic diseases characterized by metabolic disruptions, and their mutual influence can lead to adverse consequences. Epidemiological studies conducted abroad have also shown a close relationship between diabetes and NAFLD, with a significantly higher prevalence of NAFLD in individuals with abnormal glucose metabolism compared to those with normal glucose metabolism., In , the International Diabetes Federation (IDF) reported that there are approximately million adults worldwide living with diabetes, with China having an alarmingly high number of million diabetic patients, among whom the prevalence of comorbid nonalcoholic fatty liver disease ranges from % to %. Therefore, research on the co-occurrence of TDM and NAFLD is of paramount importance.
Introduction:
Type diabetes (TDM) and nonalcoholic fatty liver disease (NAFLD) are common chronic diseases characterized by metabolic disruptions, and their mutual influence can lead to adverse consequences. Epidemiological studies conducted abroad have also shown a close relationship between diabetes and NAFLD, with a significantly higher prevalence of NAFLD in individuals with abnormal glucose metabolism compared to those with normal glucose metabolism. , In , the International Diabetes Federation (IDF) reported that there…
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