Research Article: Biological Anti-IL-/IL-R Therapeutics for Chronic Obstructive Pulmonary Disease (COPD) with Specific Treatable Traits: A Real-World Retrospective Analysis
Introduction:
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease with a possible common feature across phenotypes of frequent and severe acute exacerbations of COPD (AECOPDs). AECOPDs are detrimental to overall health status, and can lead to accelerated deterioration of lung structure, extended or recurrent hospitalizations, and premature death. Moreover, AECOPDs tend to present in clusters, such that the strongest predictor of an AECOPD is a recent history of adverse lung events. Recent randomized clinical…
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