Research Article: Optimizing Temporal Summation of Heat Pain Using a Constant Contact Heat Stimulator
Introduction:
Temporal summation (TS) of pain is a C fiber-mediated phenomenon in which pain is amplified over repeated presentations of identical noxious stimuli delivered at a frequency of at least .Hz. It is the psychophysical correlate of windup, a state of temporary hyperexcitability in spinal neurons, and is used by investigators as a model for central sensitization, a prolonged state of spinal neuronal hyperexcitability that can cause hyperalgesia and allodynia. , That is, TS is used as a measure of pain and nociceptive…
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