Research Article: Secukinumab in Hidradenitis Suppurativa Patients Who Failed Adalimumab: A -Week Real-Life Study
Abstract:
Hidradenitis suppurativa (HS), is a chronic, inflammatory, recurrent and debilitating skin disease affecting hair follicles, the manifestations are characterized by inflammatory, painful and localized lesions in body districts where apocrine glands are present., The underlying pathogenic mechanism of HS is not yet known certainly follicular hyperkeratosis within the pilosebaceous-apocrine unit represents the initial lesion. New studies show new insights into the role of pro-inflammatory cytokines in the pathogenesis of HS, helping to fill some existing gaps in the knowledge of the development of this pathology.,
Introduction:
Hidradenitis suppurativa (HS), is a chronic, inflammatory, recurrent and debilitating skin disease affecting hair follicles, the manifestations are characterized by inflammatory, painful and localized lesions in body districts where apocrine glands are present. , The underlying pathogenic mechanism of HS is not yet known certainly follicular hyperkeratosis within the pilosebaceous-apocrine unit represents the initial lesion. New studies show new insights into the role of pro-inflammatory cytokines in the…
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