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Research Article: Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment

Date Published: 2024-01-06

Introduction:
Chronic kidney disease (CKD) is characterized by progressive and irreversible loss of nephrons and functional impairment and is believed to become the fifth-leading global cause of death by . CKD may increase the risks of various comorbidities, such as cardiovascular disease, bone and mineral disorder, and anemia. Although renin–angiotensin system inhibitors are used to treat kidney diseases, cardiovascular events remain a major cause of death in CKD. Current studies indicate that a deteriorated blood environment…

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