why choose us

300×250 Ad Slot

Research Article: Combined Placental Mesenchymal Stem Cells with Guided Nanoparticles Effective Against Diabetic Nephropathy in Mouse Model

Date Published: 2024-01-26

Abstract:
Diabetes is among the most prevalent diseases globally, and its incidence continues to rise. The complications associated with type diabetes, along with the adverse reactions to antidiabetic treatments, significantly affect patients’ quality of life and pose direct health risks. Therefore, preventing and delaying diabetes-related complications are essential clinical objectives., Diabetic nephropathy (DN), a primary chronic microvascular complication of diabetes, is a leading cause of end-stage renal disease. Once DN progresses to end-stage kidney disease, its complex metabolic characteristics render it more challenging to treat compared to other kidney diseases. DN’s key pathological features include glomerular sclerosis, thickening of the basement membrane, and mesangial dilation. Other features are apoptosis and loss of podocytes, renal interstitial inflammatory infiltration, and fibrosis. Although drugs that lower blood sugar or blood pressure, along with angiotensin inhibitors, can delay the onset of DN, they cannot completely prevent it. Presently, there is no cure for DN, making the exploration of novel, DN-specific treatment strategies imperative.

Introduction:
Diabetes is among the most prevalent diseases globally, and its incidence continues to rise. The complications associated with type diabetes, along with the adverse reactions to antidiabetic treatments, significantly affect patients’ quality of life and pose direct health risks. Therefore, preventing and delaying diabetes-related complications are essential clinical objectives. , Diabetic nephropathy (DN), a primary chronic microvascular complication of diabetes, is a leading cause of end-stage renal disease. Once…

Read more

300×250 Ad Slot