Research Article: Discovering and Validating Cuproptosis-Associated Marker Genes for Accurate Keloid Diagnosis Through Multiple Machine Learning Models
Abstract:
Graphical Abstract:
Introduction:
Keloid is a skin condition characterized by the proliferation of fibroblasts and the accumulation of extracellular matrix (ECM), resulting in significant impact on skin appearance and psychological well-being. Fibroblasts play a key role in the development of keloids, contributing to chronic inflammation and excessive ECM deposition. , Various fibrotic growth factors, including FGF, TGF?, VEGF, and PDGF, are known to drive fibroblast migration, invasion, and ECM deposition. , Keloid disease has a significant…
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