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Research Article: Investigation of Monogenic Diabetes Genes in Thai Children with Autoantibody Negative Diabetes Requiring Insulin

Date Published: 2024-02-14

Introduction:
Diabetes is a condition in which the body cannot make enough insulin or cannot use insulin normally. Type diabetes (TD) is subclassified as type A associated with autoantibodies to pancreatic beta cells and type B which occurs independently. Type A diabetes is characterized by chronic immune-mediated destruction of pancreatic beta cells, leading to partial or in most cases absolute insulin deficiency. Currently, the islet autoantibody testing of glutamic acid decarboxylase (GAD), the tyrosine phosphatase-like…

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