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Research Article: Serum Albumin Level Can Predict Immunotherapy Response of Neuromyelitis Optica Spectrum Disorders in the Acute Phase

Date Published: 2024-02-12

Abstract:
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system, which is characterized by recurrent longitudinal extensive myelitis (LETM) and optical neuritis (ON)., NMOSD was once thought to be a subtype of multiple sclerosis (MS). Since the discovery of immunoglobulin against aquaporin- (also known as AQP-lgG), a water channel mainly located on astrocytes in the brain, NMOSD has been confirmed to be a distinct entity. Acute attacks can cause severe morbidity or can even be fatal. Therefore, reducing the severity of acute attacks in NMOSD patients is essential.

Introduction:
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system, which is characterized by recurrent longitudinal extensive myelitis (LETM) and optical neuritis (ON). , NMOSD was once thought to be a subtype of multiple sclerosis (MS). Since the discovery of immunoglobulin against aquaporin- (also known as AQP-lgG), a water channel mainly located on astrocytes in the brain, NMOSD has been confirmed to be a distinct entity. Acute attacks can cause severe morbidity…

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